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Besides being a critical quality attribute for evaluation in stability and release testing, in vitro testing is an increasingly utilized strategy for reducing costs and modeling the behavior of actives in physiological systems. This approach minimizes unnecessary use of animal and human subjects to address issues in effective drug delivery.

  • Skin Absorption Studies
  • Bioequivalence Studies
  • Release Profiles
  • Binding Studies (Phosphate/Kinetic/Albumin etc.)
  • Pepsin Activity Studies

 

Indeed all major IVPT/IVRT systems at Sannova, are equipped with auto samplers allowing for precise and controlled measurements over long periods as required.

Sannova has experience in working in complex matrices, such as those involving simulated gastric fluids in the presence of foods, model aqueous humor, and various biological and synthetic surrogate membranes.

  • Logan Independently Variable Speed 12 Bath Dissolution Apparatus (2) with 24 Position
  • Digital Video Recording Capability
  • Distek EZFill 4500
  • Distek EZFill 6300
  • Agilent 708S with 850DS Autosampler
  • Franz Cell Apparatus: Logan DHC-6TD
  • Automated Auto Sampling Systems
  • Controlled Temperature baths (+/- 0.1oC)