Search Result()

• Bioanalytical CRO Services

  Biomarker Discovery & Validation Developing and validating assays that can be used to measure biomarkers in biological samples is crucial in biomarker discovery. Biomarkers are biological indicators of a particular disease or condition. They can be used to diagnose, monitor,...

  

• Article:
  Unlocking the Potential of Iron Nanoparticles: A Breakthrough in Quantitative Speciation Analysis

  A sponsor focused on the development of a groundbreaking iron nanoparticle – a colloidal iron oxide particle stabilized by sucrose for gastrointestinal cancers sought collaboration with Sannova Analytical for a unique approach and solution. Check out the video to know...

  

• White Paper:
  Whitepaper: CMC Guidelines for Breakthrough Therapy Drug Development, from Concept to Compliance

  This whitepaper offers a critical roadmap for navigating the complexities of regulatory compliance in biologic therapy development. Highlighting innovative strategies for chemical manufacturing and controls (CMC), this guide emphasizes laboratory practices and analytical methods to mitigate impurities, contamination, and toxicity,...

  

• White Paper:
  Whitepaper: Mitigating Risks in Oligonucleotide Therapeutic Development, Unlocking the Power of Sensitivity and Selectivity

  Oligonucleotide therapies, including small interfering RNA (siRNA), microRNA (miRNA), and inhibitory antisense oligonucleotides (ASOs), have emerged as a promising group of molecules for gene inhibition (Hu et al., 2020). These therapies hold particular potential in addressing rare diseases that lack...

  

• Article:
  Navigating Cell and Gene Therapy Protein Analysis: A Case Study in Precision and Adaptability

  At Sannova, we understand that navigating the complexities of protein analysis and therapeutic development requires adaptability and innovation. Let us share a recent collaboration where a sponsor’s gene therapeutic induces the generation of a protein with close homology with an...

  

• Privacy Policy

  This privacy notice for Sannova Analytical, LLC (“We,” “Us,” or “Our”), describes how and why we might collect, store, use, and/or share (“Process”) your information when you use our services (“Services”), such as when you: Visit our website at sannova.net...

  

• White Paper:
  Whitepaper: Mastering HRMS for Preclinical Toxicology in Diverse Matrices

  Unlock the highest level of confidence in your preclinical toxicology studies by harnessing the capabilities of High-Resolution Mass Spectrometry (HRMS). While traditional methods lack the sensitivity needed to distinguish subtle differences in mass-to-charge ratios (m/z) between ions, particularly on low-resolution...

  

• White Paper:
  eBook: Extractables and Leachables, Regulatory Trends & Future Prospects

  In the ever-evolving landscape of pharmaceuticals, the scrutiny surrounding extractables and leachables has become increasingly pivotal. As regulatory frameworks continually adapt to advancements in technology and scientific understanding, professionals in the pharmaceutical industry find themselves at the intersection of innovation...

  

• White Paper:
  Whitepaper: High Resolution Methods for Clinical Biomarker Validation

  Discover how high-resolution biomarker assays such as Meso Scale Discovery (MSD) and advanced Mass Spectrometry (MS) go beyond the limitations of traditional ELISA assays. Gain comparative insights into the superiority of high-resolution methods, and how they overcome central challenges in...

  

• White Paper:
  Addressing Bioanalytical Method Development Challenges from Preclinical to Clinical Trials

  At Sannova, we recognize the intricate and often non-linear nature of R&D and drug development, standing ready to navigate the challenges alongside our clients. One such journey involved a client developing a nanoparticle-bound immunosuppressant. They started with a rat study...