In this AAPS eChalk Talk, our speakers will explore how Ion Mobility Spectrometry (IMS) is revolutionizing mass spectrometry by enhancing sensitivity and selectivity. They will discuss the advances in mass spectrometry and increase in throughput speed, specifically as it pertains...
Biomarker Discovery & Validation Developing and validating assays that can be used to measure biomarkers in biological samples is crucial in biomarker discovery. Biomarkers are biological indicators of a particular disease or condition. They can be used to diagnose, monitor,...
A sponsor focused on the development of a groundbreaking iron nanoparticle – a colloidal iron oxide particle stabilized by sucrose for gastrointestinal cancers sought collaboration with Sannova Analytical for a unique approach and solution. Check out the video to know...
This whitepaper offers a critical roadmap for navigating the complexities of regulatory compliance in biologic therapy development. Highlighting innovative strategies for chemical manufacturing and controls (CMC), this guide emphasizes laboratory practices and analytical methods to mitigate impurities, contamination, and toxicity,...
Oligonucleotide therapies, including small interfering RNA (siRNA), microRNA (miRNA), and inhibitory antisense oligonucleotides (ASOs), have emerged as a promising group of molecules for gene inhibition (Hu et al., 2020). These therapies hold particular potential in addressing rare diseases that lack...
At Sannova, we understand that navigating the complexities of protein analysis and therapeutic development requires adaptability and innovation. Let us share a recent collaboration where a sponsor’s gene therapeutic induces the generation of a protein with close homology with an...
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Unlock the highest level of confidence in your preclinical toxicology studies by harnessing the capabilities of High-Resolution Mass Spectrometry (HRMS). While traditional methods lack the sensitivity needed to distinguish subtle differences in mass-to-charge ratios (m/z) between ions, particularly on low-resolution...
In the ever-evolving landscape of pharmaceuticals, the scrutiny surrounding extractables and leachables has become increasingly pivotal. As regulatory frameworks continually adapt to advancements in technology and scientific understanding, professionals in the pharmaceutical industry find themselves at the intersection of innovation...
Discover how high-resolution biomarker assays such as Meso Scale Discovery (MSD) and advanced Mass Spectrometry (MS) go beyond the limitations of traditional ELISA assays. Gain comparative insights into the superiority of high-resolution methods, and how they overcome central challenges in...